PMS2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all PMS2 蛋白
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PMS2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PMS2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PMS2 蛋白
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PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) protein (GST tag)
PMS2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 763-862) protein (GST tag)PMS2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) protein (Strep Tag)Crystallography grade PMS2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-859) protein (Strep Tag)Crystallography grade PMS2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
- 别名
- Pms2 (PMS2 产品)
- 别名
- HNPCC4 Protein, PMS2CL Protein, PMSL2 Protein, AW555130 Protein, Pmsl2 Protein, PMS1 homolog 2, mismatch repair system component Protein, PMS1 homolog2, mismatch repair system component Protein, mismatch repair endonuclease PMS2 Protein, PMS2 Protein, Pms2 Protein, LOC463257 Protein, LOC107984056 Protein
- 背景
- The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC also known as Lynch syndrome) and Turcot syndrome.
- 分子量
- 95.6 kDa
- NCBI登录号
- NP_000526
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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