Paxillin Protein (PXN) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(2 references)-
- 抗原 See all Paxillin (PXN) 蛋白
- Paxillin (PXN)
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This Paxillin protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human Paxillin / PXN (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PXN 蛋白
-
Paxillin (PXN) (AA 1-22) protein (GST tag)
PXN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Paxillin (PXN) (AA 1-262) protein (GST tag)PXN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Paxillin (PXN) (AA 1-591) protein (Strep Tag)Crystallography grade PXN 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Paxillin (PXN) (AA 1-591) protein (Strep Tag)Crystallography grade PXN 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
: "Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3." in: Cell reports, Vol. 15, Issue 8, pp. 1660-72, (2016) (PubMed).
: "Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature." in: Histochemistry and cell biology, Vol. 142, Issue 3, pp. 245-56, (2014) (PubMed).
-
: "Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3." in: Cell reports, Vol. 15, Issue 8, pp. 1660-72, (2016) (PubMed).
-
- 抗原
- Paxillin (PXN)
- 别名
- Paxillin,pxn (PXN 产品)
- 别名
- AW108311 Protein, AW123232 Protein, Pax Protein, CG18061 Protein, CG18576 Protein, CG31794 Protein, CT40481 Protein, CT42454 Protein, DPaxillin Protein, DPxn Protein, DPxn37 Protein, Dmel\\CG31794 Protein, Dpax Protein, DpaxA Protein, PDLP Protein, dPax Protein, pax Protein, wu:fw71f12 Protein, PXN Protein, LOC100220858 Protein, paxillin Protein, Paxillin Protein, paxillin S homeolog Protein, paxillin a Protein, PXN Protein, Pxn Protein, Pax Protein, pxn.S Protein, pxna Protein, LOC696336 Protein, pxn Protein
- 背景
- This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
- 分子量
- 60.8 kDa
- NCBI登录号
- NP_002850
- 途径
- MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
-
