NEDD4-2 Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)
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- 抗原 See all NEDD4-2 (NEDD4L) 蛋白
- NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant B
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NEDD4-2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NEDD4L (transcript variant b) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NEDD4L 蛋白
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E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-911) protein (GST tag)
NEDD4L 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-100) protein (GST tag)NEDD4L 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-1004) protein (Strep Tag)Crystallography grade NEDD4L 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 2-975) protein (His tag)Crystallography grade NEDD4L 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
- 别名
- Nedd4l (NEDD4L 产品)
- 别名
- NEDD4-2 Protein, NEDD4.2 Protein, RSP5 Protein, hNEDD4-2 Protein, nedd4 Protein, nedd4-2 Protein, NEDD4 Protein, Nedd4-2 Protein, 1300012C07Rik Protein, Nedd4b Protein, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase Protein, NEDD4L Protein, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog Protein, neural precursor cell expressed, developmentally down-regulated gene 4-like Protein, NEDD4L Protein, LOC776799 Protein, nedd4l.S Protein, Nedd4l Protein
- 背景
- This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- 分子量
- 98 kDa
- NCBI登录号
- NP_001138436
- 途径
- Negative Regulation of Transporter Activity
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