MASP1 Protein (Transcript Variant 3) (His tag)
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- 抗原 See all MASP1 蛋白
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 3
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MASP1 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human MASP-1 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Top Product
- Discover our top product MASP1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 缓冲液
- Supplied as a 0.2 μM filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 别名
- Masp-1 (MASP1 产品)
- 别名
- AW048060 Protein, CCPII Protein, Crarf Protein, Masp1/3 Protein, 3MC1 Protein, CRARF Protein, CRARF1 Protein, MAP1 Protein, MASP Protein, MASP3 Protein, MAp44 Protein, PRSS5 Protein, RaRF Protein, mannan-binding lectin serine peptidase 1 Protein, mannan binding lectin serine peptidase 1 Protein, Masp1 Protein, MASP1 Protein
- 背景
- This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
- 分子量
- 80.68kD
- NCBI登录号
- NP_001027019
- 途径
- Complement System
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