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KPNA2 Protein (Myc-DYKDDDDK Tag)

KPNA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2724403
发货至: 中国
  • 抗原 See all KPNA2 蛋白
    KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 1
    资源
    • 3
    • 2
    • 2
    HEK-293 Cells
    标记
    This KPNA2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human KPNA2 / Importin alpha-2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KPNA2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
    别名
    Kpna2,importin alpha-2 (KPNA2 产品)
    别名
    IPOA1 Protein, QIP2 Protein, RCH1 Protein, SRP1alpha Protein, ima2 Protein, importin Protein, 2410044B12Rik Protein, PTAC58 Protein, Rch1 Protein, ipoa1 Protein, kpna2 Protein, qip2 Protein, rch1 Protein, srp1alpha Protein, hm:zeh0389 Protein, hm:zeh0389r Protein, zgc:113902 Protein, zgc:86945 Protein, karyopherin subunit alpha 2 Protein, importin subunit alpha-2 Protein, Importin subunit alpha-2 Protein, karyopherin (importin) alpha 2 Protein, karyopherin alpha-2 subunit like L homeolog Protein, karyopherin alpha 2 (RAG cohort 1, importin alpha 1) Protein, KPNA2 Protein, EDI_246290 Protein, EDI_335040 Protein, ima2 Protein, Kpna2 Protein, kpna2.L Protein, kpna2 Protein
    背景
    The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants.
    分子量
    57.7 kDa
    NCBI登录号
    NP_002257
    途径
    M Phase, Protein targeting to Nucleus
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