IL-6 Protein (Myc-DYKDDDDK Tag)
Quick Overview for IL-6 Protein (Myc-DYKDDDDK Tag) (ABIN2723738)
抗原
See all IL-6 (IL6) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This IL-6 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Interleukin-6 / IL6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL-6 (IL6) (Interleukin 6 (IL6))
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别名
- Interleukin-6,il6
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背景
- This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
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分子量
- 20.8 kDa
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NCBI登录号
- NP_000591
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途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
抗原
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