Insulin Protein (INS) (Myc-DYKDDDDK Tag)
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Quick Overview for Insulin Protein (INS) (Myc-DYKDDDDK Tag) (ABIN2723506)
抗原
See all Insulin (INS) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This Insulin protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Insulin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Insulin (INS) protein
INS 宿主: 人 宿主: 酵母菌 Recombinant Greater than 95 % as determined by SDS-PAGE.
Insulin (INS) (AA 1-110) protein (GST tag)INS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin (INS) (AA 25-54), (AA 90-110) (Active) protein (His tag)INS 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Insulin (INS)
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别名
- Insulin
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背景
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
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分子量
- 9.3 kDa
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NCBI登录号
- NP_000198
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途径
- NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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