INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all INPP5D 蛋白
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This INPP5D protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human INPP5D (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product INPP5D 蛋白
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Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 1-1189) protein (Strep Tag)
Crystallography grade INPP5D 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 1-1191) protein (Strep Tag)Crystallography grade INPP5D 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
- 别名
- Inpp5d (INPP5D 产品)
- 别名
- INPP5D Protein, 256.t00004 Protein, 13.t00027 Protein, ship Protein, ship1 Protein, AI323613 Protein, SHIP Protein, SHIP-1 Protein, SHIP1 Protein, s-SHIP Protein, SIP-145 Protein, hp51CN Protein, inositol polyphosphate-5-phosphatase D Protein, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Protein, inositol polyphosphate 5-phosphatase Protein, inositol polyphosphate-5-phosphatase D L homeolog Protein, INPP5D Protein, LOC100446045 Protein, inpp5d Protein, EHI_159880 Protein, EHI_153490 Protein, inpp5d.L Protein, LOC100380693 Protein, Inpp5d Protein
- 背景
- This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants.
- 分子量
- 133 kDa
- NCBI登录号
- NP_005532
- 途径
- TCR Signaling, BCR Signaling, Warburg Effect
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