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INPP5D 蛋白

(Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
INPP5D Protein (AA 1-1189) (Strep Tag) INPP5D Protein (AA 1-1189) (Strep Tag) INPP5D Protein (AA 1-1189) (Strep Tag) (ABIN3095410)

Crystallography grade INPP5D 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

INPP5D Protein (AA 1-1191) (Strep Tag) INPP5D Protein (AA 1-1191) (Strep Tag) INPP5D Protein (AA 1-1191) (Strep Tag) (ABIN3137223)

Crystallography grade INPP5D 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2723485)

INPP5D 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

INPP5D 蛋白 by Grade

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INPP5D 蛋白 by Origin

Find INPP5D 蛋白 for a variety of species such as anti-Human INPP5D, anti-Mouse INPP5D. The species listed below are among those available. Click on a link to go to the corresponding products.

INPP5D 蛋白 by Source

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INPP5D 蛋白 by 蛋白类型

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INPP5D 蛋白 by 应用范围

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Popular INPP5D 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095410
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3137223
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723485
Quantity 20 μg
Datasheet Datasheet

Aliases for INPP5D 蛋白

inositol polyphosphate-5-phosphatase D (INPP5D) 蛋白
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100446045) 蛋白
inositol polyphosphate-5-phosphatase D (inpp5d) 蛋白
inositol polyphosphate 5-phosphatase (EHI_159880) 蛋白
inositol polyphosphate 5-phosphatase (EHI_153490) 蛋白
inositol polyphosphate-5-phosphatase D L homeolog (inpp5d.L) 蛋白
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100380693) 蛋白
inositol polyphosphate-5-phosphatase D (Inpp5d) 蛋白
13.t00027 蛋白
256.t00004 蛋白
AI323613 蛋白
hp51CN 蛋白
INPP5D 蛋白
s-SHIP 蛋白
ship 蛋白
SHIP 蛋白
SHIP-1 蛋白
ship1 蛋白
SHIP1 蛋白
SIP-145 蛋白
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