HLA-DMB Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all HLA-DMB 蛋白
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This HLA-DMB protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human HLA class II DM beta / HLA-DMB protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HLA-DMB 蛋白
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Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) protein (GST tag)
HLA-DMB 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 19-218) protein (His tag)Crystallography grade HLA-DMB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 19-263) protein (rho-1D4 tag)Crystallography grade HLA-DMB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
- 别名
- Hla Class II Dm Beta,hla-Dmb (HLA-DMB 产品)
- 别名
- RING7 Protein, D6S221E Protein, RT1.DMb Protein, RT1.Mb Protein, MHC-DMB Protein, major histocompatibility complex, class II, DM beta Protein, RT1 class II, locus DMb Protein, HLA-DMB Protein, RT1-DMb Protein, PATR-DMB Protein
- 背景
- HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
- 分子量
- 27.1 kDa
- NCBI登录号
- NP_002109
- 途径
- Cancer Immune Checkpoints
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