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HLA-E Protein (Myc-DYKDDDDK Tag)

HLA-E 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722835
发货至: 中国
  • 抗原 See all HLA-E 蛋白
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 1
    资源
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This HLA-E protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human HLA class I alpha E / HLA-E protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HLA-E 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    别名
    Hla Class I alpha E,hla-E (HLA-E 产品)
    别名
    EA1.2 Protein, EA2.1 Protein, HLA-6.2 Protein, MHC Protein, QA1 Protein, major histocompatibility complex, class I, E Protein, HLA-E Protein, PATR-E Protein
    背景
    HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
    分子量
    37.8 kDa
    NCBI登录号
    NP_005507
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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