HLA-E 产品
(HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
Categories
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008].
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Featured HLA-E Categories
HLA-E 抗体
High quality antibodies with extensive validation data.
HLA-E ELISA试剂盒
Reliable ELISA kits for a wide range of species.
HLA-E 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HLA-E 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
- (4)
Cat. No.
ABIN674334
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Non-Human Primate
Application
FACS, IP, IHC (p)
Validations
- (5)
- (4)
Cat. No.
ABIN94354
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (4)
Cat. No.
ABIN516523
Quantity
50 μg
Datasheet
Datasheet
Recommended HLA-E ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6956585
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962563
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN809033
Quantity
96 tests
Datasheet
Datasheet
Recommended HLA-E 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123351
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1989653
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3081441
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our HLA-E Products
: "Soluble-HLA-E: A follow up biomarker in Takayasu arteritis, independent of HLA-E genotype." in: International journal of rheumatic diseases, Vol. 21, Issue 2, pp. 532-540, (2018) (PubMed).: "Alamandine attenuates sepsis-associated cardiac dysfunction via inhibiting MAPKs signaling pathways." in: Life sciences, Vol. 206, pp. 106-116, (2018) (PubMed).
: "High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer." in: Oncoimmunology, Vol. 6, Issue 1, pp. e1264562, (2017) (PubMed).
: "Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients." in: Cellular immunology, Vol. 293, Issue 1, pp. 10-6, (2015) (PubMed).
: "MicroRNA editing facilitates immune elimination of HCMV infected cells." in: PLoS pathogens, Vol. 10, Issue 2, pp. e1003963, (2014) (PubMed).
: "Profound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma." in: Cancer research, Vol. 71, Issue 16, pp. 5412-22, (2011) (PubMed).
: "Serum soluble HLA-E in melanoma: a new potential immune-related marker in cancer." in: PLoS ONE, Vol. 6, Issue 6, pp. e21118, (2011) (PubMed).
: "CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children." in: Journal of human genetics, Vol. 56, Issue 2, pp. 161-5, (2011) (PubMed).
: "Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells." in: Neoplasia (New York, N.Y.), Vol. 13, Issue 9, pp. 822-30, (2011) (PubMed).
: "Glycodelin A suppresses the cytolytic activity of CD8+ T lymphocytes." in: Molecular immunology, Vol. 47, Issue 15, pp. 2458-66, (2010) (PubMed).
Synonyms and alternative names related to HLA-E
major histocompatibility complex, class I, E (HLA-E), major histocompatibility complex, class I, E (PATR-E), EA1.2, EA2.1, HLA-6.2, MHC, QA1Protein level used designations for HLA-E
- HLA class I histocompatibility antigen, E alpha chain
- HLA class I histocompatibility antigen, alpha chain E
- MHC HLA-E alpha-1
- MHC HLA-E alpha-2.1
- MHC class I antigen E
- lymphocyte antigen
- patr class I histocompatibility antigen, alpha chain E
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