电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

HLA-DRB3 产品

(Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))

Categories

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured HLA-DRB3 Categories

HLA-DRB3 抗体

High quality antibodies with extensive validation data.

HLA-DRB3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HLA-DRB3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN516514
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (3)
Cat. No. ABIN7258926
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7155605
Quantity 100 μg
Datasheet Datasheet

Recommended HLA-DRB3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306765
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3092151
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3114182
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HLA-DRB3 Products

Alappat, Volkland, Peter: "Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site." in: The Journal of biological chemistry, Vol. 278, Issue 43, pp. 41585-8, (2003) (PubMed).

Hua, Sohn, Kang, Cado, Winoto: "A function of Fas-associated death domain protein in cell cycle progression localized to a single amino acid at its C-terminal region." in: Immunity, Vol. 18, Issue 4, pp. 513-21, (2003) (PubMed).

Synonyms and alternative names related to HLA-DRB3

major histocompatibility complex, class II, DR beta 3 (HLA-DRB3), major histocompatibility complex, class II, DRB3 (BOLA-DRB3), BLA-DRB3, Bota-DRB01, Bota-DRB02, Bota-DRB04, Bota-DRB07, Bota-DRB21, Bota-DRB22, HLA-DR3B, LA-DRB

Protein level used designations for HLA-DRB3

  • DR7
  • HLA class II histocompatibility antigen, DR beta 3 chain
  • HLA class II histocompatibility antigen, DRB1-7 beta chain
  • MHC class II HLA-DR beta 3 chain
  • MHC class II antigen DR beta 3 chain
  • MHC class II antigen DRB3
  • human leucocyte antigen DRB3
  • BoLA-DRB3.2
  • DR beta-chain antigen binding domain
  • DR-beta chain MHC class II
  • MHC class II DR beta chain
  • MHC class II DRB3
  • MHC class II antigen BoLA-DRB3
  • MHC class II antigen beta chain
  • MHC class II leukocyte antigen BoLA-DRB3
  • MHC(BoLA) class II DR-beta chain
  • histocompatibility complex, class II, DR beta 3
  • leukocyte antigen DRB3
  • major histocompatibility complex class II DR-beta chain
  • major histocompatibility complex, class II, DR beta 3
  • major histocompatibility complex, class II, DRB3
You are here:
客服