HAAO Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all HAAO 蛋白
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This HAAO protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human HAAO protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HAAO 蛋白
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3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (His tag)
HAAO 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (GST tag)HAAO 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) protein (GST tag)HAAO 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) protein (His tag)HAAO 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by SDS-PAGE
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (Strep Tag)Crystallography grade HAAO 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- 别名
- Haao (HAAO 产品)
- 别名
- Afu2g17450 Protein, 0610007K21Rik Protein, 0610012J07Rik Protein, 3-HAO Protein, 3-HAOxase Protein, 3HAO Protein, zgc:103585 Protein, HAO Protein, 3-hydroxyanthranilate 3,4-dioxygenase Protein, 3-hydroxyanthranilate 3,4-dioxygenase L homeolog Protein, SPO1774 Protein, CNB05620 Protein, AFUA_2G17450 Protein, Bcep18194_C7641 Protein, Kfla_5491 Protein, Micau_4935 Protein, RBRH_03005 Protein, Krodi_1278 Protein, haao Protein, HAAO Protein, Haao Protein, haao.L Protein
- 背景
- 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.
- 分子量
- 32.4 kDa
- NCBI登录号
- NP_036337
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