HAAO 蛋白
(3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq, Jul 2008].
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16 results
custom-made
HAAO
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
HAAO
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Aliases for HAAO 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (SPO1774) 蛋白3-hydroxyanthranilate 3,4-dioxygenase (CNB05620) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (AFUA_2G17450) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (Bcep18194_C7641) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (Kfla_5491) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (Micau_4935) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (RBRH_03005) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (Krodi_1278) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (haao) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (HAAO) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase (Haao) 蛋白
3-hydroxyanthranilate 3,4-dioxygenase L homeolog (haao.L) 蛋白
3-HAO 蛋白
3-HAOxase 蛋白
3HAO 蛋白
0610007K21Rik 蛋白
0610012J07Rik 蛋白
Afu2g17450 蛋白
HAO 蛋白
zgc:103585 蛋白
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