HACE1 蛋白
(HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB (By similarity).
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custom-made
HACE1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
HACE1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for HACE1 蛋白
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) 蛋白HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (hace1) 蛋白
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 L homeolog (hace1.L) 蛋白
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (Hace1) 蛋白
1700042J16Rik 蛋白
A730034A22Rik 蛋白
BC025474 蛋白
HACE1 蛋白
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