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Haptoglobin beta Chain 蛋白

(Haptoglobin beta Chain (HP))

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Haptoglobin beta Chain (HP) 蛋白 (ABIN1000924)

HP 宿主: 大肠杆菌（E. Coli） Recombinant DB, IHC, ELISA, WB

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Popular Haptoglobin beta Chain 蛋白

Product

Reactivity

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Haptoglobin beta Chain (HP) 蛋白

Reactivity

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1000924

Quantity 10 μg

Datasheet Datasheet

Aliases for Haptoglobin beta Chain 蛋白

haptoglobin (HP) 蛋白
haptoglobin (Hp) 蛋白
BP 蛋白
HP-1 蛋白
HP2ALPHA2 蛋白
HPA1S 蛋白

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