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HAS1 蛋白

(Hyaluronan Synthase 1 (HAS1))
Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase. [provided by RefSeq, Jul 2008].
Hyaluronan Synthase 1 (HAS1) (AA 1-583) protein (rho-1D4 tag) Hyaluronan Synthase 1 (HAS1) (AA 1-583) protein (rho-1D4 tag) Hyaluronan Synthase 1 (HAS1) (AA 1-583) protein (rho-1D4 tag) (ABIN3123028)

Crystallography grade HAS1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Hyaluronan Synthase 1 (HAS1) (AA 74-399) protein (His tag) Hyaluronan Synthase 1 (HAS1) (AA 74-399) protein (His tag) Hyaluronan Synthase 1 (HAS1) (AA 74-399) protein (His tag) (ABIN3081679)

Crystallography grade HAS1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Hyaluronan Synthase 1 (HAS1) (AA 73-404) protein (His tag) Hyaluronan Synthase 1 (HAS1) (AA 73-404) protein (His tag) Hyaluronan Synthase 1 (HAS1) (AA 73-404) protein (His tag) (ABIN3123029)

Crystallography grade HAS1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

HAS1 蛋白 by Grade

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HAS1 蛋白 by Origin

Find HAS1 蛋白 for a variety of species such as anti-Human HAS1, anti-Rat HAS1, anti-Mouse HAS1. The species listed below are among those available. Click on a link to go to the corresponding products.

HAS1 蛋白 by Source

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HAS1 蛋白 by 蛋白类型

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HAS1 蛋白 by 应用范围

Find HAS1 蛋白 validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HAS1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093006
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009895
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7083426
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7083425
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6120523
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast (Saccharomyces Cerevisiae)
Validations
Cat. No. ABIN6120077
Quantity 100 μg
Datasheet Datasheet

Aliases for HAS1 蛋白

hyaluronan synthase 1 (has1) 蛋白
hyaluronan synthase 1 (HAS1) 蛋白
hyaluronan synthase 1 (Has1) 蛋白
hyaluronan synthase 1 S homeolog (has1.S) 蛋白
dg42 蛋白
HAS 蛋白
shas1 蛋白
Xhas1 蛋白
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