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FKBP1A Protein (Transcript Variant 12A) (Myc-DYKDDDDK Tag)

FKBP1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2721206
发货至: 中国
  • 抗原 See all FKBP1A 蛋白
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 12A
    宿主
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 13
    • 5
    • 1
    • 1
    HEK-293 Cells
    标记
    This FKBP1A protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human FKBP1A / FKBP12 (transcript variant 12A) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FKBP1A 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    别名
    Fkbp1a,fkbp12 (FKBP1A 产品)
    别名
    12kDa Protein, FKBP12 Protein, FKBP12-T1 Protein, FKBP12-T2 Protein, Fkbp Protein, Fkbp1 Protein, mFKBP1 Protein, mFKBP12 Protein, FKBP-12 Protein, FKBP-1A Protein, FKBP1 Protein, Rotamase Protein, Fkbp12 Protein, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 Protein, ATFKBP12 Protein, FK506-binding protein 12 Protein, IMMUNOPHILIN Protein, MSJ1.19 Protein, MSJ1_19 Protein, PKC12 Protein, PKCI2 Protein, PPIASE Protein, FKBP1B Protein, Fkbp2 Protein, fj02g10 Protein, zgc:73373 Protein, wu:fj02g10 Protein, FKBP1A Protein, Bmfkbp13 Protein, zgc:103752 Protein, FK506 binding protein 1a Protein, FK506 binding protein 1A Protein, FK506-binding protein Protein, FK506-binding protein 12 Protein, FK506 binding protein 1Aa Protein, FK506 binding protein 1C Protein, FK506-binding protein 59 Protein, FK506 binding protein like Protein, FK506 binding protein 1A L homeolog Protein, FK506 binding protein 1Ab Protein, Fkbp1a Protein, FKBP1A Protein, Fkbp12 Protein, FKBP12 Protein, fkbp1aa Protein, FKBP1C Protein, EHI_180160 Protein, LOC5573443 Protein, Fkbp13 Protein, FKBPL Protein, fkbp1a.L Protein, fkbp1ab Protein
    背景
    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.
    分子量
    11.8 kDa
    NCBI登录号
    NP_463460
    途径
    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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