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FGF8 Protein (His tag)

FGF8 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP
产品编号 ABIN2721099
发货至: 中国
  • 抗原 See all FGF8 蛋白
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 4
    • 2
    • 1
    • 1
    资源
    • 16
    • 2
    大肠杆菌(E. Coli)
    标记
    This FGF8 protein is labelled with His tag.
    应用范围
    Standard (STD), Antibody Production (AbP)
    产品特性
    • Recombinant human FGF8 (full length, N-term HIS tag, transcript variant F) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FGF8 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    50 mM Tris, pH 8.0, 500 mM NaCl, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    别名
    Fgf8 (FGF8 产品)
    别名
    Aigf Protein, Fgf-8 Protein, AIGF Protein, FGF-8 Protein, HBGF-8 Protein, HH6 Protein, KAL6 Protein, fibroblast growth factor 8 Protein, Fgf8 Protein, FGF8 Protein
    背景
    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
    分子量
    25.3 kDa
    NCBI登录号
    NP_149353
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
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