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EXOSC7 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

EXOSC7 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2720634
发货至: 中国
  • 抗原 See all EXOSC7 蛋白
    EXOSC7 (Exosome Component 7 (EXOSC7))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 4
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This EXOSC7 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human EXOSC7 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product EXOSC7 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    EXOSC7 (Exosome Component 7 (EXOSC7))
    别名
    Exosc7 (EXOSC7 产品)
    别名
    EXOSC7 Protein, zgc:110717 Protein, EAP1 Protein, RRP42 Protein, Rrp42p Protein, hRrp42p Protein, p8 Protein, 2610002K22Rik Protein, AV212732 Protein, mKIAA0116 Protein, exosome component 7 Protein, exosome component 7 S homeolog Protein, exosc7 Protein, EXOSC7 Protein, exosc7.S Protein, Exosc7 Protein
    背景
    Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. [UniProtKB/Swiss-Prot Function]
    分子量
    31.6 kDa
    NCBI登录号
    NP_055819
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