BAG4 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all BAG4 蛋白
- BAG4 (BCL2-Associated Athanogene 4 (BAG4))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This BAG4 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human BAG4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BAG4 蛋白
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BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) protein (GST tag)
BAG4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
BCL2-Associated Athanogene 4 (BAG4) (AA 231-340) protein (GST tag)BAG4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) protein (Strep Tag)Crystallography grade BAG4 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) protein (Strep Tag)Crystallography grade BAG4 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- BAG4 (BCL2-Associated Athanogene 4 (BAG4))
- 别名
- Bag4 (BAG4 产品)
- 别名
- BAG-4 Protein, SODD Protein, BAG4 Protein, fd20a04 Protein, wu:fd20a04 Protein, si:dkey-220o5.3 Protein, 2410112I15Rik Protein, ATBAG4 Protein, BCL-2-associated athanogene 4 Protein, BCL2 associated athanogene 4 Protein, BCL2-associated athanogene 4 Protein, BCL-2-associated athanogene 4 Protein, BAG4 Protein, Bag4 Protein, bag4 Protein
- 背景
- The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
- 分子量
- 49.4 kDa
- NCBI登录号
- NP_004865
- 途径
- Regulation of Actin Filament Polymerization
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