APEX1 Protein (Transcript Variant 1)
Quick Overview for APEX1 Protein (Transcript Variant 1) (ABIN2714788)
抗原
See all APEX1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 1
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产品特性
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- Recombinant human APEX1 / REF-1 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
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Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) protein (GST tag)
APEX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 97-195) protein (His-IF2DI Tag)APEX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) protein (His tag)APEX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) protein (T7 tag)APEX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90% by SDS-PAGE SDS
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 32-318) protein (His tag)APEX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 10 mM HEPES, 100 mM KCl, 50 % Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
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别名
- Apex1,ref-1
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背景
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene all encode the same protein.
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分子量
- 35.6 kDa
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NCBI登录号
- NP_001632
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途径
- DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
抗原
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