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PDGFRB Protein (Myc-DYKDDDDK Tag)

PDGFRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, STD, PI Active
产品编号 ABIN2713419
发货至: 中国
  • 抗原 See all PDGFRB 蛋白
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 24
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    • 1
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    资源
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    HEK-293 Cells
    标记
    This PDGFRB protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Functional Studies (Func), Standard (STD), Protein Interaction (PI)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human CD140b / PDGFRB protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Biological Activity Comment
    PDGFRB activity verified in a biochemical assay:,PDGFRB activity verified in a biochemical assay:
    Top Product
    Discover our top product PDGFRB 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    > 50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    别名
    Cd140b,pdgfrb (PDGFRB 产品)
    别名
    AI528809 Protein, CD140b Protein, PDGFR-1 Protein, Pdgfr Protein, CD140B Protein, IBGC4 Protein, JTK12 Protein, PDGFR Protein, PDGFR1 Protein, platelet derived growth factor receptor, beta polypeptide Protein, platelet derived growth factor receptor beta Protein, Pdgfrb Protein, PDGFRB Protein
    背景
    This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
    分子量
    123.8 kDa
    NCBI登录号
    NP_002600
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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