PDGFRB Protein (His-Avi Tag,Biotin)
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- 抗原 See all PDGFRB 蛋白
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PDGFRB protein is labelled with His-Avi Tag,Biotin.
- 序列
- Leu33-Phe530
- 纯度
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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- Discover our top product PDGFRB 蛋白
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Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-530) protein (His-Avi Tag)
PDGFRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-531) protein (His tag)PDGFRB 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 561-1106) (Active) protein (GST tag)PDGFRB 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) protein (GST tag)PDGFRB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (His tag)PDGFRB 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-532) protein (His tag)PDGFRB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (Fc Tag)PDGFRB 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-532) protein (His tag)Crystallography grade PDGFRB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 554-1106) protein (His tag)Crystallography grade PDGFRB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 32-531) protein (His tag)Crystallography grade PDGFRB 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- 别名
- PDGF R beta (PDGFRB 产品)
- 别名
- AI528809 Protein, CD140b Protein, PDGFR-1 Protein, Pdgfr Protein, CD140B Protein, IBGC4 Protein, JTK12 Protein, PDGFR Protein, PDGFR1 Protein, platelet derived growth factor receptor, beta polypeptide Protein, platelet derived growth factor receptor beta Protein, Pdgfrb Protein, PDGFRB Protein
- 背景
- JTK12, PDGF R beta, PDGFR, PDGFR1, PDGFRB, CD140B, PDGFR-2, PDGFR-β,PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
- 分子量
- 59 kDa. Due to glycosylation, the protein migrates to 78-115 kDa based on Tris-Bis PAGE result.
- UniProt
- P09619
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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