CBFA2T2 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- 抗原 See all CBFA2T2 蛋白
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 4
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CBFA2T2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CBFA2T2 (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CBFA2T2 蛋白
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Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 201-304) protein (GST tag)
CBFA2T2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 1-614) protein (GST tag)CBFA2T2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 1-604) protein (Strep Tag)Crystallography grade CBFA2T2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 1-594) protein (Strep Tag)Crystallography grade CBFA2T2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- 别名
- Cbfa2t2 (CBFA2T2 产品)
- 别名
- MTGR1 Protein, A430091M07 Protein, C330013D05Rik Protein, Cbfa2t2h Protein, EHT Protein, ZMYND3 Protein, p85 Protein, XETOR Protein, cbfa2t2-a Protein, CBFA2/RUNX1 translocation partner 2 Protein, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) Protein, CBFA2/RUNX1 translocation partner 2 L homeolog Protein, Cbfa2t2 Protein, CBFA2T2 Protein, cbfa2t2.L Protein
- 背景
- In acute myeloid leukemia, especially in the M2 subtype, the t(821)(q22q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5&apos-region of the RUNX1 (AML1) gene fused to the 3&apos-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
- 分子量
- 63.7 kDa
- NCBI登录号
- NP_001034798
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