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CRH Protein (His tag)

CRH 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712520
发货至: 中国
  • 抗原 See all CRH 蛋白
    CRH (Corticotropin Releasing Hormone (CRH))
    蛋白类型
    Recombinant
    宿主
    • 6
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    资源
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    大肠杆菌(E. Coli)
    标记
    This CRH protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Corticoliberin (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CRH 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CRH (Corticotropin Releasing Hormone (CRH))
    别名
    Corticoliberin (CRH 产品)
    别名
    CRF Protein, Gm1347 Protein, crf Protein, crh Protein, zgc:101864 Protein, CRH Protein, corticoliberin Protein, crhb Protein, crh.1-a Protein, crha Protein, corticotropin releasing hormone Protein, corticotropin releasing hormone b Protein, corticotropin releasing hormone S homeolog Protein, corticotropin releasing hormone L homeolog Protein, Crh Protein, CRH Protein, crhb Protein, crh Protein, crh.S Protein, crh.L Protein
    背景
    This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer&aposs disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
    分子量
    18.9 kDa
    NCBI登录号
    NP_000747
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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