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CRH 产品

(Corticotropin Releasing Hormone (CRH))

Categories

Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].

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Featured CRH Categories

CRH 抗体

High quality antibodies with extensive validation data.

CRH ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CRH 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CRH 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7429697
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN739430
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (3)
Cat. No. ABIN514593
Quantity 100 μg
Datasheet Datasheet

Recommended CRH ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
  • (4)
Cat. No. ABIN6574093
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (9)
Cat. No. ABIN956064
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963683
Quantity 96 tests
Datasheet Datasheet

Recommended CRH 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350331
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350330
Quantity 25 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505513
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CRH Products

Son, Zhang, Shannonhouse, Ishida, Gomez, Kim: "Mast-cell-specific receptor mediates alcohol-withdrawal-associated headache in male mice." in: Neuron, (2023) (PubMed).

Zhang, Li, Liu, Zhang, Xue, Li, Cheng, Cao: "Contribution of DNA methylation in chronic stress-induced cardiac remodeling and arrhythmias in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 11, pp. 12240-12252, (2020) (PubMed).

de Bem, Okinga, Ognibene, da Costa, Santos, Soares, Silva, da Rocha, Isnardo Fernandes, Fraga, Filgueiras, Manhães, Soares de Moura, Resende: "Anxiolytic and antioxidant effects of Euterpe oleracea Mart. (açaí) seed extract in adult rat offspring submitted to periodic maternal separation." in: Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme, Vol. 45, Issue 11, pp. 1277-1286, (2020) (PubMed).

Aguiniga, Yang, Yaggie, Schaeffer, Klumpp: "ACYLOXYACYL HYDROLASE MODULATES DEPRESSIVE-LIKE BEHAVIORS THROUGH ARYL HYDROCARBON RECEPTOR." in: American journal of physiology. Regulatory, integrative and comparative physiology, (2019) (PubMed).

Chauhan, Kapoor, Prabha Singh, Gupta, Chand Meena, Tulsawani, Nanda, Bala Singh: "Heat stress-induced neuroinflammation and aberration in monoamine levels in hypothalamus are associated with temperature dysregulation." in: Neuroscience, Vol. 358, pp. 79-92, (2018) (PubMed).

Riezzo, Chimienti, Clemente, DAttoma, Orlando, Mammone Rinaldi, Russo: "Colonic Transit Time and Gut Peptides in Adult Patients with Slow and Normal Colonic Transit Constipation." in: BioMed research international, Vol. 2017, pp. 3178263, (2018) (PubMed).

Huo, Zeng, Zeng, Cheng, Li, Luo, Wang, Zhou, Fang, Li, Niu, Wei, Xie: "Microbiota Modulate Anxiety-Like Behavior and Endocrine Abnormalities in Hypothalamic-Pituitary-Adrenal Axis." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 489, (2018) (PubMed).

Bromek, Rysz, Haduch, Wójcikowski, Daniel: "Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 46, Issue 6, pp. 786-793, (2018) (PubMed).

Lee, Shim, Lee, Hahm: "Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder." in: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, Vol. 22, Issue 5, pp. 525-538, (2018) (PubMed).

Zhao, Niu, Wang, Yang, Du, Wei, Li: "The depressive-like behaviors of chronic unpredictable mild stress-treated mice, ameliorated by Tibetan medicine Zuotai: involvement in the hypothalamic-pituitary-adrenal (HPA) axis pathway." in: Neuropsychiatric disease and treatment, Vol. 14, pp. 129-141, (2018) (PubMed).

Synonyms and alternative names related to CRH

corticotropin releasing hormone (Crh), corticotropin releasing hormone (CRH), corticotropin releasing hormone b (crhb), corticotropin releasing hormone (crh), corticotropin releasing hormone S homeolog (crh.S), corticotropin releasing hormone L homeolog (crh.L), corticoliberin, CRF, crf, crh, CRH, crh.1-a, crha, crhb, Gm1347, zgc:101864

Protein level used designations for CRH

  • corticoliberin
  • corticotropin releasing factor
  • corticotropin-releasing factor
  • corticotropin-releasing hormone
  • CRF
  • corticotropin releasing hormone
  • corticotrophin-releasing factor
  • corticotropin releasing hormone, gene 1
  • corticotropin-releasing factor b
  • corticotropin releasing hormone b
  • Corticotropin-releasing hormone
  • corticotropin releasing hormone a
  • corticotropin-releasing factor a
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