KAT2B Protein (AA 715-829) (His tag,DYKDDDDK Tag)
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- 抗原 See all KAT2B 蛋白
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 715-829
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This KAT2B protein is labelled with His tag,DYKDDDDK Tag.
- 应用范围
- Binding Studies (Bind), Screening Assay (ScA)
- 产品特性
- The peptide corresponding to amino acids 715 - 829 that contains the bromodomain sequences of PCAF (accession number NM_003884.4) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 19.8 kDa. It shows binding specificity for acetylated H3K9, H3K14, H3K36, H4K8, H4K16, H4K20 and TATK50.
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- Discover our top product KAT2B 蛋白
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K(lysine) Acetyltransferase 2B (KAT2B) (AA 1864-2068) protein (His-IF2DI Tag)
KAT2B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
K(lysine) Acetyltransferase 2B (KAT2B) (AA 636-832) protein (His-IF2DI Tag)KAT2B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
K(lysine) Acetyltransferase 2B (KAT2B) (AA 431-832) protein (His tag)KAT2B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) protein (GST tag)KAT2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
K(lysine) Acetyltransferase 2B (KAT2B) (AA 731-832) protein (GST tag)KAT2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
K(lysine) Acetyltransferase 2B (KAT2B) protein (DYKDDDDK Tag)KAT2B 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
K(lysine) Acetyltransferase 2B (KAT2B) protein (Myc-DYKDDDDK Tag)KAT2B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Recombinant PCAF (715-829) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
- 限制
- 仅限研究用
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- 注意事项
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- 储存条件
- -80 °C
- 储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- 抗原
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- 别名
- PCAF (KAT2B 产品)
- 别名
- PCAF Protein, pcaf Protein, si:ch211-1j13.2 Protein, zgc:161980 Protein, gb:dq017634 Protein, im:7156024 Protein, CAF Protein, P Protein, P/CAF Protein, A930006P13Rik Protein, AI461839 Protein, AW536563 Protein, Pcaf Protein, p/CAF Protein, lysine acetyltransferase 2B Protein, K(lysine) acetyltransferase 2B Protein, K(lysine) acetyltransferase 2A Protein, KAT2B Protein, kat2b Protein, kat2a Protein, Kat2b Protein
- 背景
- P300/CBP-associated factor (PCAF), also known as K (lysine) acetyltransferase 2B (KAT2B), is a transcriptional coactivator associated with p53 that contains acetyltransferase and E3 ubiquitin ligase domains as well as a bromodomain for interaction with other proteins. The bromodomain functions as a 'reader' of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. PCAF competes with E1A for binding to p300/CBP, which associate with various sequence-specific factors involved in cell growth and/or differentiation, including c-Jun and the adenoviral oncoprotein E1A. PCAF exerts histone acetyltransferase activity in association with core histones (H3 and H4) and with nucleosome core particles, and functions to promote transcriptional activation. PCAF has also been shown to inhibit cell cycle progression and to counteract the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, PCAF is recruited by the viral protein TAT to regulate TAT's transactivating activity and may help induce chromatin remodeling of proviral genes.
- 分子量
- 19.8 kDa
- 途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
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