AOC3 Protein (AA 27-763)
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- 抗原 See all AOC3 蛋白
- AOC3 (Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 27-763
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Multiplex Assay (MA)
- 纯度
- >98 % , as determined by Coomassie stained SDS-PAGE.
- 内毒素水平
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Less than 0.1 ng per μg of protein.
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Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 1-763) protein (GST tag)
AOC3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 351-450) protein (GST tag)AOC3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Biological activity: Human VAP-1 is able to produce hydrogen peroxide during the oxidation of benzylamine. The specific activity is > 16 pMoles/min/μg of VAP-1.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- For maximum results, quick spin vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. It is recommended to further dilute in a buffer containing a carrier protein such as 0.1 % BSA and store working aliquots at -20 °C to -80 °C.
- 缓冲液
- Lyophilized
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Unopened vial can be stored at -20°C or -70°C.
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- 抗原
- AOC3 (Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3))
- 别名
- VAP-1 (AOC3 产品)
- 别名
- HPAO Protein, SSAO Protein, VAP-1 Protein, VAP1 Protein, aoc2 Protein, BOLAO Protein, amine oxidase, copper containing 3 Protein, amine oxidase, copper containing 3 L homeolog Protein, AOC3 Protein, aoc3.L Protein, Aoc3 Protein
- 背景
- VAP-1 is a type II cell adhesion membrane protein belonging to the copper/topaquinone oxidase family. Functionally, VAP-1 is a nonclassical inflammation-inducible endothelial molecule involved in leukocyte-subtype-specific rolling under physiological shear. Molecularly, VAP-1 belongs to a special class of cell surface amino oxidases. The enzymatic reaction itself and the biologically active end products can potentially regulate the adhesive status of the vessel wall. Thus, VAP-1 is an ectoenzyme that has inter-related adhesive and enzymatic functions in regulating physiological trafficking and inflammation. Inhibition of VAP-1 can protect against inflammation related damage to certain injured tissues. This protein is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Additionally, VAP-1 can function as a significant prognostic marker for certain cancers and cardiovascular diseases.
- 分子量
- The 737 amino acid recombinant protein has a predicted molecular mass of approximately 84 kDa. Recombinant VAP-1 is a mixture of monomers and disulfide linked homodimers. The predicted N-terminal amino acid is Gly.
- 途径
- Feeding Behaviour
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