AOC3 Protein (Fc Tag)
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- 抗原 See all AOC3 蛋白
- AOC3 (Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This AOC3 protein is labelled with Fc Tag.
- 原理
- Recombinant Human VAP-1/AOC3 Protein (Fc Tag)
- 序列
- Arg28-Asn763
- 产品特性
- Recombinant Human Membrane primary amine oxidase is produced by our Mammalian expression system and the target gene encoding Arg28-Asn763 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AOC3 蛋白
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Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 1-763) protein (GST tag)
AOC3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 351-450) protein (GST tag)AOC3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 27-763) protein (His tag)Crystallography grade AOC3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 28-765) protein (His tag)Crystallography grade AOC3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 2-763) protein (rho-1D4 tag)Crystallography grade AOC3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) (AA 2-765) protein (rho-1D4 tag)Crystallography grade AOC3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,500 mM NaCl, pH 8.0.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- AOC3 (Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3))
- 别名
- VAP-1/AOC3 (AOC3 产品)
- 别名
- HPAO Protein, SSAO Protein, VAP-1 Protein, VAP1 Protein, aoc2 Protein, BOLAO Protein, amine oxidase, copper containing 3 Protein, amine oxidase, copper containing 3 L homeolog Protein, AOC3 Protein, aoc3.L Protein, Aoc3 Protein
- 背景
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Background: Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflammation. This rise in metabolic products contributes to generating advanced glycation end-products and oxidative stress along with the monoamine detoxification in the organism. It is highly expressed on the endothelium of the lung and trachea, and absent from leukocytes and epithelial cells. Membrane-bound VAP-1 releases an active, soluble form of the protein, which may be conducive to increased inflammation and the progression of many vascular disorders. In particular, elevation of VAP-1 activity and the increased enzymatic-mediated deamination is proposed to play a role in renal and vascular disease, oxidative stress, acute and chronic hyperglycemia, and diabetes complications.
Synonym: Membrane primary amine oxidase, Copper amine oxidase, Semicarbazide-sensitive amine oxidase, Vascular adhesion protein 1, AOC3, VAP-1, SSAO, HPAO,VAP1
- 分子量
- 108.5 kDa
- UniProt
- Q16853
- 途径
- Feeding Behaviour
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