FGF7 Protein (AA 32-194)
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- 抗原 See all FGF7 蛋白
- FGF7 (Fibroblast Growth Factor 7 (FGF7))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 32-194
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Biochemical Assay (BCA)
- 纯度
- >95 % , as determined by Coomassie stained SDS-PAGE and HPLC analysis.
- 内毒素水平
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Less than 0.1 ng per μg of protein.
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- Discover our top product FGF7 蛋白
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Fibroblast Growth Factor 7 (FGF7) (Active) protein
FGF7 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag)FGF7 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag,Biotin)FGF7 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag)FGF7 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 7 (FGF7) (AA 1-97) protein (GST tag)FGF7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag)Crystallography grade FGF7 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag)Crystallography grade FGF7 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Biological activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml corresponding to a specific activity of ≥ 1 x 105 units/mg.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- For maximum results, quick spin vial prior to opening. Reconstitute in 20 mM Tris, pH 8.0 to a concentration of ≤1.0 mg/mL. Do not vortex. It is recommended to further dilute in a buffer containing a carrier protein such as 0.1 % BSA and store working aliquots at -20 °C to -80 °C.
- 缓冲液
- Lyophilized, carrier-free.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Unopened vial can be stored at -20°C or -70°C.
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- 抗原
- FGF7 (Fibroblast Growth Factor 7 (FGF7))
- 别名
- KGF (FGF7 产品)
- 别名
- HBGF-7 Protein, KGF Protein, Kgf Protein, kgf Protein, FGF-7 Protein, fgf7 Protein, fibroblast growth factor 7 Protein, fibroblast growth factor 7 L homeolog Protein, FGF7 Protein, Fgf7 Protein, fgf7 Protein, fgf7.L Protein
- 背景
- KGF is a heparin binding growth factor secreted by cells of mesenchymal origin. KGF acts in a paracrine manner by binding exclusively to a splicing variant of FGF receptor 2, FGFR2-IIIB. FGFR-IIIB is predominatly expressed by epithelial cells. This suggests that KGF may play an important role in mesenchymal-epithelial communication. KGF can stimulate proliferation, migration, and differentiation of epithelial cells in a variety of tissues. In skin, KGF can be strongly upregulated in dermal fibroblasts after skin injury. KGF can induce keratinocyte proliferation and migration. KGF can also protect epithelial cells from reactive oxygen species. In liver, KGF is required for adult liver regeneration. In brain, KGF is important for inhibitory synapse formation in the hippocampus. KGF-deficient mice are prone to epileptic seizures induced by chemical kindling in adults. KGF signaling is also important for hair follicle development. Injection of recombinant KGF into adult athymic nude mice can induce dose-dependent hair growth. In lung, KGF can protect animals from oxidant-induced injury. Taken together, KGF is a potential target for epithelial tissue repair.
- 分子量
- The 163 amino acid recombinant protein has a predicted molecular mass of approximately 18.9 kDa. The predicted N-terminal amino acid is Cys.
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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