IL-17A/F Protein (AA 26-158, AA 29-161, Heterodimer)
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- 抗原 See all IL-17A/F 蛋白
- IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
- 蛋白类型
- Recombinant
- 产品特性
- Heterodimer, AA 26-158, AA 29-161
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- ELISA, Biochemical Assay (BCA)
- 纯度
- Purity is > 98 % , as determined by Coomassie stained SDS-PAGE.
- Top Product
- Discover our top product IL-17A/F 蛋白
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Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 26-158) protein (His-Avi Tag)
IL-17A/F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 26-158) protein (His-Avi Tag,Biotin)IL-17A/F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) protein (His-Avi Tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag,AVI tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant
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- 应用备注
- Optimal working dilution should be determined by the investigator.,Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Prior to use, reconstitute the lyophilized powder with 0.2 mLof PBS containing a carrier protein (e.g., 1 % BSA, protease free), pH 7.4. Re-cap vial, vortex. Allow the reconstituted standard to sit at room temperature for 15 minutes, vortex again to mix completely. The reconstituted standard stock solution can be aliquoted into polypropylene vials and stored at -70 °C for up to one month.
- 缓冲液
- Lyophilized in sterile-filtered PBS, pH 7.2, containing 1 % BSA.
- 注意事项
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.
- 储存条件
- 4 °C
- 储存方法
- Upon receipt, store unopened vials between 2°C and 8°C immediately and use within 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
- 别名
- IL-17A/F (IL-17A/F 产品)
- 别名
- il17-5 Protein, si:ch211-63o20.2 Protein, interleukin 17a/f3 Protein, il17a/f3 Protein
- 背景
- IL-17A/F is part of the IL-17 cytokine family which consists of six structurally related proteins (IL-17A, B, C, D, E, and F). IL-17A is expressed primarily by Th17 cells, a subset of CD4 T cells. IL-17F is most closely related to IL-17A. The two molecules share 50 % amino acid sequence homology. Like IL-17A, IL-17F mRNA and protein have been detected in Th17 cells. IL-17F and IL-17A exist as homodimers, adopting a cysteine knot motif formed through the interactions of four cysteines, one of which is responsible for the interchain bonding. IL-17F and IL-17A can form both homodimeric and heterodimeric proteins when expressed in a recombinant system and all forms of the recombinant proteins have in vitro functional activity. Mouse Th17 cells secret IL-17A/F as well as the homodimers IL-17A and IL-17F. IL-17A/F induces IL-6 and KC (CXCL1) production in mouse fibroblast and macrophages. IL-17A/F signals through IL-17A and TRAF6.
- 分子量
- 30 kDa
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