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IL-17A/F Protein (His-Avi Tag,Biotin)

IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
产品编号 ABIN7275003
发货至: 中国
  • 抗原 See all IL-17A/F 蛋白
    IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 3
    • 1
    资源
    • 4
    • 3
    • 1
    HEK-293 Cells
    标记
    This IL-17A/F protein is labelled with His-Avi Tag,Biotin.
    序列
    Gly24-Ala155(IL-17A) & Arg31-Gln163(IL-17F)
    纯度
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Biotinylated Human IL-17A&F, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 0.19μg/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product IL-17A/F 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
    别名
    IL-17A&F (IL-17A/F 产品)
    别名
    il17-5 Protein, si:ch211-63o20.2 Protein, interleukin 17a/f3 Protein, il17a/f3 Protein
    背景
    IL-17A,Interleukin-17A,CTLA-8,IL-17,IL-17F,IL24,ML-1,Interleukin-17F,Interleukin-17A (IL-17A), also known as CTLA-8, is a 15-20 kDa glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
    分子量
    15.1 kDa (IL-17A)&17.5 kDa (IL-17F). Due to glycosylation, the protein migrates to 16 kDa&27 kDa based on Tris-Bis PAGE result.
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