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TGFBR2 Protein (Fc Tag)

TGFBR2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
产品编号 ABIN2566963
发货至: 中国
  • 抗原 See all TGFBR2 蛋白
    TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
    蛋白类型
    Recombinant
    宿主
    • 21
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    • 1
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    资源
    • 12
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    HEK-293 Cells
    标记
    This TGFBR2 protein is labelled with Fc Tag.
    应用范围
    Western Blotting (WB)
    产品特性

    Fusion tag: C-Fc Tag

    纯度
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product TGFBR2 蛋白
  • 应用备注
    This recombinant protein can be used for WB. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM tris, 100 mM glycine, pH 7.5
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
    别名
    TGFR2 (TGFBR2 产品)
    别名
    AAT3 Protein, FAA3 Protein, LDS1B Protein, LDS2B Protein, MFS2 Protein, RIIC Protein, TAAD2 Protein, TGFR-2 Protein, TGFbeta-RII Protein, 1110020H15Rik Protein, AU042018 Protein, DNIIR Protein, RIIDN Protein, TBR-II Protein, TbetaR-II Protein, TbetaRII Protein, TGFBR2 Protein, TBETA-RII Protein, TGFBRII Protein, TGF-beta 2 Protein, Tgfbr2T Protein, cb537 Protein, tgfbr2 Protein, wu:fj05c10 Protein, zgc:110498 Protein, transforming growth factor beta receptor 2 Protein, transforming growth factor, beta receptor II Protein, transforming growth factor, beta receptor 2 Protein, transforming growth factor beta receptor 2b Protein, TGFBR2 Protein, Tgfbr2 Protein, tgfbr2b Protein
    背景
    TGF-beta receptor type-2 (TGFBR2 or TGFR-2) is also known as TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TbetaR-II, TGFβR2, which is a homodimer or heterohexamer, belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. TGFR2 / TGFBR2 binds TGF-β1 / TGFB1 and TGF-β3 / TGFB3 with high affinity and TGF-β2 / TGFB2 with a much lower affinity. This type I I receptor forms a heterodimeric complex with type I receptor and is essential for signal transduction. Upon ligand binding, the TGFR2 autophosphorylates its cytoplasmic domain and subsequently phosphorylates the downstream molecules which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.
    分子量
    42 kDa
    基因ID
    7048
    NCBI登录号
    NP_003233
    UniProt
    P37173
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