CD79b Protein (Fc Tag)
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- 抗原 See all CD79b (CD79B) 蛋白
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD79b protein is labelled with Fc Tag.
- 应用范围
- Western Blotting (WB)
- 产品特性
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Fusion tag: C-Fc Tag
- 纯度
- >92 % as determined by SDS-PAGE.
- Top Product
- Discover our top product CD79B 蛋白
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- 应用备注
- This recombinant protein can be used for WB. For research use only.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM tris, 100 mM glycine, pH 7.5
- 储存条件
- -80 °C,-20 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- 抗原
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- 别名
- CD79 B (CD79B 产品)
- 别名
- B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein
- 背景
- B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
- 分子量
- 41.8 kDa
- 基因ID
- 974
- NCBI登录号
- NP_000617
- UniProt
- P40259
- 途径
- BCR Signaling
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