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CD79b Protein (Fc Tag)

CD79B 宿主: 人 宿主: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB
产品编号 ABIN2566441
发货至: 中国
  • 抗原 See all CD79b (CD79B) 蛋白
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    蛋白类型
    Recombinant
    宿主
    • 17
    • 5
    • 2
    • 2
    • 2
    资源
    • 14
    • 6
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    • 2
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    HEK-293 Cells
    标记
    This CD79b protein is labelled with Fc Tag.
    应用范围
    Western Blotting (WB)
    产品特性

    Fusion tag: C-Fc Tag

    纯度
    >92 % as determined by SDS-PAGE.
    Top Product
    Discover our top product CD79B 蛋白
  • 应用备注
    This recombinant protein can be used for WB. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM tris, 100 mM glycine, pH 7.5
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    别名
    CD79 B (CD79B 产品)
    别名
    B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein
    背景
    B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
    分子量
    41.8 kDa
    基因ID
    974
    NCBI登录号
    NP_000617
    UniProt
    P40259
    途径
    BCR Signaling
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