ACVRL1 Protein (His tag)
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- 抗原 See all ACVRL1 蛋白
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ACVRL1 protein is labelled with His tag.
- 应用范围
- Western Blotting (WB)
- 产品特性
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Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is typically 1-3 ng/mL in the presence of 2 ng/mL of rhBMP9.
- 纯度
- >97 % as determined by SDS-PAGE.
- Top Product
- Discover our top product ACVRL1 蛋白
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Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-118) protein (His tag)
ACVRL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Activin A Receptor Type II-Like 1 (ACVRL1) protein (Fc Tag)ACVRL1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-503) protein (GST tag)ACVRL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-119) protein (GST tag)ACVRL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor Type II-Like 1 (ACVRL1) (Active) protein (His tag,Fc Tag)ACVRL1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Activin A Receptor Type II-Like 1 (ACVRL1) (Active) protein (His tag,Fc Tag)ACVRL1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 应用备注
- This recombinant protein can be used for WB. For research use only.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -80 °C,-20 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- 抗原
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- 别名
- ALK 1 (ACVRL1 产品)
- 别名
- ACVRL1 Protein, vgb Protein, alk1 Protein, zehn1109 Protein, hm:zehn1109 Protein, ACVRLK1 Protein, ALK-1 Protein, ALK1 Protein, HHT Protein, HHT2 Protein, ORW2 Protein, SKR3 Protein, TSR-I Protein, R-3 Protein, R3 Protein, SETHKIR Protein, AI115505 Protein, AI427544 Protein, Acvrlk1 Protein, Alk1 Protein, activin A receptor like type 1 Protein, activin A receptor type II-like 1 Protein, activin A receptor, type II-like 1 Protein, ACVRL1 Protein, acvrl1 Protein, Acvrl1 Protein
- 背景
- Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ALK1 gene. ALK1 is a receptor in the TGF beta signaling pathway. ALK1 protein is a receptor in the TGF beta signaling pathway. It plays an important role in vascular development, remodeling, and pathologic angiogenesis, play a role in stabilizing angiogenic vessels and contribute to resistance to anti-VEGF therapies, ALK1 blockade may represent an effective therapeutic opportunity complementary to the current antiangiogenic modalities in the clinic. Recently, researcher found that, ALK1-Fc inhibited BMP9-mediated Id-1 expression in human umbilical vein endothelial cells and inhibited cord formation by these cells on a Matrigel substrate, in a chick chorioallantoic membrane assay, ALK1-Fc reduced vascular endothelial growth factor-, fibroblast growth factor-, and BMP10-mediated vessel formation, and ALK1-Fc treatment reduced tumor burden in mice receiving orthotopic grafts of MCF7 mammary adenocarcinoma cells.
- 分子量
- 12.3 kDa
- 基因ID
- 94
- NCBI登录号
- NP_000011
- UniProt
- P37023
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