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ACVRL1 Protein (Fc Tag)

ACVRL1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320736
发货至: 中国
  • 抗原 See all ACVRL1 蛋白
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    蛋白类型
    Recombinant
    宿主
    • 12
    • 4
    • 2
    • 1
    • 1
    小鼠
    资源
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This ACVRL1 protein is labelled with Fc Tag.
    原理
    Recombinant Mouse ALK-1/ACVRL1 Protein (Fc Tag)
    序列
    Asp23-Pro119
    产品特性
    Recombinant Mouse Activin Receptor-like Kinase 1 is produced by our Mammalian expression system and the target gene encoding Asp23-Pro119 is expressed with a Fc tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ACVRL1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    别名
    ALK-1/ACVRL1 (ACVRL1 产品)
    别名
    ACVRL1 Protein, vgb Protein, alk1 Protein, zehn1109 Protein, hm:zehn1109 Protein, ACVRLK1 Protein, ALK-1 Protein, ALK1 Protein, HHT Protein, HHT2 Protein, ORW2 Protein, SKR3 Protein, TSR-I Protein, R-3 Protein, R3 Protein, SETHKIR Protein, AI115505 Protein, AI427544 Protein, Acvrlk1 Protein, Alk1 Protein, activin A receptor like type 1 Protein, activin A receptor type II-like 1 Protein, activin A receptor, type II-like 1 Protein, ACVRL1 Protein, acvrl1 Protein, Acvrl1 Protein
    背景

    Background: Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angiogenesis during embryogenesis, wound healing, and tumor growth. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. ALK-1 is mainly expressed in endothelial cells regulating proliferation and migration in vitro and angiogenesis in vivo. Mutations in ALK-1 as well as in endoglin are associated with hereditary hemorrhagic telangiectasia (HHT), suggesting ALK-1 plays a critical role for in the control of blood vessel development or repair.

    Synonym: Serine/threonine-protein kinase receptor R3, SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I, ACVRL1, activin A receptor type II-like 1, activin A receptor

    分子量
    38.1 kDa
    UniProt
    Q61288
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