ACVR2B Protein (His tag)
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- 抗原 See all ACVR2B 蛋白
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ACVR2B protein is labelled with His tag.
- 应用范围
- Western Blotting (WB)
- 产品特性
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Measured by its ability to inhibit Activin Ainduced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0. 2-0. 5 μg/mL of recombinant human ActivinR-IIB will inhibit 50 % of the biological response due to 3 ng/mL of rhActivin A.
Fusion tag: C-His Tag
- 纯度
- >97 % as determined by SDS-PAGE.
- Top Product
- Discover our top product ACVR2B 蛋白
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Activin A Receptor, Type IIB (ACVR2B) (AA 161-512) (Active) protein (GST tag)
ACVR2B 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Activin A Receptor, Type IIB (ACVR2B) (AA 1-303) protein (GST tag)ACVR2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IIB (ACVR2B) (AA 21-120) protein (GST tag)ACVR2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IIB (ACVR2B) (Active) protein (His tag,Fc Tag)ACVR2B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Activin A Receptor, Type IIB (ACVR2B) (Active) protein (His tag)ACVR2B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE Active
Activin A Receptor, Type IIB (ACVR2B) (AA 159-512) protein (His tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-137) protein (His tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 159-536) protein (His tag)Crystallography grade ACVR2B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-137) protein (His tag)Crystallography grade ACVR2B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-512) protein (rho-1D4 tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- This recombinant protein can be used for WB. For research use only.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -80 °C,-20 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- 抗原
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- 别名
- ACVR2B (ACVR2B 产品)
- 别名
- ACVR2B Protein, XAR1 Protein, actr-iib Protein, actriib Protein, ACTRIIB Protein, ActR-IIB Protein, HTX4 Protein, ActRIIB Protein, actr2b Protein, actrIIb Protein, wu:fj97d11 Protein, activin A receptor type 2B Protein, activin A receptor type 2B L homeolog Protein, activin A receptor type 2Ba Protein, activin receptor IIB Protein, ACVR2B Protein, acvr2b Protein, acvr2b.L Protein, Acvr2b Protein, acvr2ba Protein
- 背景
- Activin receptor type-2B (ACVR2B) is also known as ActR-IIB and MGC116908, ACVR2B is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. Defects in ACVR2B are the cause of visceral heterotaxy autosomal type 4 (HTX4).
- 分子量
- 14.5 kDa
- 基因ID
- 93
- NCBI登录号
- NP_001097
- UniProt
- Q13705
- 途径
- Hormone Transport, Cancer Immune Checkpoints
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