Endonuclease G Protein (ENDOG) (AA 51-140) (His tag,Strep II tag)
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- 抗原 See all Endonuclease G (ENDOG) 蛋白
- Endonuclease G (ENDOG)
- 蛋白类型
- Recombinant
- 产品特性
- AA 51-140
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Endonuclease G protein is labelled with His tag,Strep II tag.
- 应用范围
- Western Blotting (WB), ELISA, Mass Spectrometry (MS)
- 纯度
- ~95 %
- Top Product
- Discover our top product ENDOG 蛋白
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Endonuclease G (ENDOG) (AA 23-212) protein (His-IF2DI Tag)
ENDOG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Endonuclease G (ENDOG) (AA 50-297) protein (GST tag)ENDOG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endonuclease G (ENDOG) (AA 49-297) protein (His tag)Crystallography grade ENDOG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endonuclease G (ENDOG) (AA 45-294) protein (His tag)Crystallography grade ENDOG 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endonuclease G (ENDOG) (AA 1-294) (Active) protein (His tag,GST tag)ENDOG 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 1X PBS containing 0.1 % SDS and 0.02 % NaN
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- Endonuclease G (ENDOG)
- 别名
- EndoG (ENDOG 产品)
- 别名
- CG8862 Protein, Dmel\\CG8862 Protein, Tb08.10J17.140 Protein, Tb08.10J17.90 Protein, TBC1D13 Protein, endog Protein, ENDOG Protein, wu:fb79c08 Protein, zgc:110020 Protein, Endonuclease G Protein, endonuclease G Protein, putative endonuclease G Protein, endonuclease G, mitochondrial Protein, endonuclease G L homeolog Protein, EndoG Protein, Tc00.1047053506867.10 Protein, Tb927.8.4040 Protein, Tb927.8.4090 Protein, LBRM_10_0750 Protein, LMJF_10_0610 Protein, NAEGRDRAFT_78507 Protein, ENDOG Protein, endog Protein, eNDOG Protein, LOC100529218 Protein, Endog Protein, endog.L Protein
- 背景
- The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribo-nuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD (1-3). EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans (2). EndoG also cleaves DNA in vitro (4).
- 分子量
- 15 kDa (Calculated)
- 基因ID
- 2021
- OMIM
- 24638471
- UniProt
- Q14249
- 途径
- Apoptosis
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