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ATG7 Protein (AA 450-698) (His tag)

ATG7 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant ~95 % WB, ELISA, MS, Neut
产品编号 ABIN2468252
发货至: 中国
  • 抗原 See all ATG7 蛋白
    ATG7 (ATG7 Autophagy Related 7 (ATG7))
    蛋白类型
    Recombinant
    产品特性
    AA 450-698
    宿主
    • 7
    • 3
    • 1
    小鼠
    资源
    • 6
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This ATG7 protein is labelled with His tag.
    应用范围
    Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
    纯度
    ~95 %
    Top Product
    Discover our top product ATG7 蛋白
  • 应用备注
    This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    1X PBS containing 10 % glycerol
    注意事项
    Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    储存条件
    -80 °C
    储存方法
    Store in working aliquots at -70 °C.
  • 抗原
    ATG7 (ATG7 Autophagy Related 7 (ATG7))
    别名
    ATG7 (ATG7 产品)
    别名
    APG7-LIKE Protein, APG7L Protein, GSA7 Protein, D8 Protein, UBA1B Protein, UBE1L Protein, UBE2 Protein, Ube1l Protein, 1300004C08Rik Protein, AO090001000744 Protein, atg7 Protein, 1810013K23Rik Protein, Agp7 Protein, Apg7l Protein, Atg7l Protein, ATAPG7 Protein, ATATG7 Protein, ATG7 Protein, AUTOPHAGY 7 Protein, AUTOPHAGY-RELATED 7 Protein, K15I22.10 Protein, K15I22_10 Protein, autophagy related 7 Protein, ubiquitin like modifier activating enzyme 7 Protein, ubiquitin-like modifier activating enzyme 7 Protein, autophagy-related protein 7 Protein, Autophagy-related protein 7 Protein, Apg7p Protein, ThiF family protein Protein, ubiquitin-like conjugating enzyme Atg7 Protein, ATG7 Protein, UBA7 Protein, Uba7 Protein, ANI_1_3368024 Protein, AOR_1_1338164 Protein, PTRG_02236 Protein, PAAG_00287 Protein, PITG_12537 Protein, atg7 Protein, Atg7 Protein, APG7 Protein
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1 (3). Another member of the autophagy family of proteins is APG7 which was identified in yeast as a ubiquitin-E1-like enzyme , this function is conserved in the mammalian homolog (4). In mammalian cells, APG7 is essential for autophagy conjugation systems, autophagosome formation, starvation-induced bulk degradation of proteins and organelles (5). It has been suggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death (6).
    分子量
    30 kDa (Calculated)
    基因ID
    74244
    OMIM
    37589293
    UniProt
    Q9D906
    途径
    Response to Water Deprivation, Autophagy
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