ATG12 Protein (AA 101-141) (His tag)
ATG12
宿主: 人, 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
~95 %
ELISA, WB, MS, Neut
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- 抗原 See all ATG12 蛋白
- ATG12 (Autophagy Related 12 (ATG12))
- 蛋白类型
- Recombinant
- 产品特性
- AA 101-141
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宿主
- 人, 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ATG12 protein is labelled with His tag.
- 应用范围
- ELISA, Western Blotting (WB), Mass Spectrometry (MS), Neutralization (Neut)
- 纯度
- ~95 %
- Top Product
- Discover our top product ATG12 蛋白
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Autophagy Related 12 (ATG12) (AA 1-74) protein (GST tag)
ATG12 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Autophagy Related 12 (ATG12) (AA 1-140) protein (GST tag)ATG12 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 1X PBS containing 0.1 % SDS
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- ATG12 (Autophagy Related 12 (ATG12))
- 别名
- ATG12 (ATG12 产品)
- 别名
- APG12 Protein, APG12L Protein, FBR93 Protein, HAPG12 Protein, Apg12l Protein, AUTOPHAGY 12 Protein, AUTOPHAGY 12 B Protein, CG10861 Protein, Dmel\\CG10861 Protein, atg12 Protein, ATG12 Protein, apg12 Protein, DDBDRAFT_0185323 Protein, DDBDRAFT_0191412 Protein, DDB_0185323 Protein, DDB_0191412 Protein, 4931423H11Rik Protein, A330058M13Rik Protein, Atg12l Protein, AO090001000593 Protein, autophagy related 12 Protein, Ubiquitin-like superfamily protein Protein, Atg12p Protein, autophagy protein Protein, ubiquitin-like protein ATG12B Protein, autophagy associated protein Atg12 Protein, Autophagy-related 12 Protein, ATG12 autophagy related 12 homolog (S. cerevisiae) Protein, ATG12 autophagy related 12 homolog (S. cerevisiae) pseudogene Protein, autophagy associated ubiquitin-like modifier Atg12 Protein, hypothetical protein Protein, Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) Protein, autophagy protein 12 Protein, autophagy related 12 S homeolog Protein, autophagy-related protein 12 Protein, ATG12 Protein, Atg12 Protein, APG12B Protein, APG12 Protein, LOC9321066 Protein, apg12 Protein, atg12 Protein, LOC743425 Protein, CAALFM_C113950CA Protein, atg12.S Protein, ANI_1_922094 Protein, AOR_1_1064164 Protein
- 背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1 (3). ATG12, another member of the autophagy protein family, forms a conjugate with ATG5 , this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy (4). This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells (5). ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7 (6).
- 分子量
- 10 kDa (Calculated)
- 基因ID
- 9140
- OMIM
- 17366729
- UniProt
- O94817, Q9CQY1
- 途径
- Autophagy
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