TGFBR2 Protein (AA 23-159) (Fc Tag)
(1 reference)-
- 抗原 See all TGFBR2 蛋白
- TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-159
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TGFBR2 protein is labelled with Fc Tag.
- 序列
- AA 23-159
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product TGFBR2 蛋白
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Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 24-159) protein (mFc-Avi Tag)
TGFBR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) protein (Fc Tag)TGFBR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 24-159) protein (mFc-Avi Tag,Biotin)TGFBR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 194-567) (Active) protein (GST tag)TGFBR2 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 23-159) (Active) protein (His tag,AVI tag,Biotin)TGFBR2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) protein (His tag)TGFBR2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 1-334) protein (GST tag)TGFBR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 1-567) protein (GST tag)TGFBR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 62-165) protein (GST tag)TGFBR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) protein (Fc Tag)TGFBR2 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." in: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).
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: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." in: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).
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- 抗原
- TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
- 别名
- TGFBR2 (TGFBR2 产品)
- 别名
- AAT3 Protein, FAA3 Protein, LDS1B Protein, LDS2B Protein, MFS2 Protein, RIIC Protein, TAAD2 Protein, TGFR-2 Protein, TGFbeta-RII Protein, 1110020H15Rik Protein, AU042018 Protein, DNIIR Protein, RIIDN Protein, TBR-II Protein, TbetaR-II Protein, TbetaRII Protein, TGFBR2 Protein, TBETA-RII Protein, TGFBRII Protein, TGF-beta 2 Protein, Tgfbr2T Protein, cb537 Protein, tgfbr2 Protein, wu:fj05c10 Protein, zgc:110498 Protein, transforming growth factor beta receptor 2 Protein, transforming growth factor, beta receptor II Protein, transforming growth factor, beta receptor 2 Protein, transforming growth factor beta receptor 2b Protein, TGFBR2 Protein, Tgfbr2 Protein, tgfbr2b Protein
- 背景
- TGF-beta receptor type-2 (TGFBR2 or TGFR-2) is also known as TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TbetaR-II, TGFβR2, which is a homodimer or heterohexamer, belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. TGFR2 / TGFBR2 binds TGF-β1 / TGFB1 and TGF-β3 / TGFB3 with high affinity and TGF-β2 / TGFB2 with a much lower affinity. This type I I receptor forms a heterodimeric complex with type I receptor and is essential for signal transduction. Upon ligand binding, the TGFR2 autophosphorylates its cytoplasmic domain and subsequently phosphorylates the downstream molecules which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.
- 分子量
- 42.1 kDa
- NCBI登录号
- NP_003233
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