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SCARB1 Protein (AA 33-443) (Fc Tag)

SCARB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181726
发货至: 中国
  • 抗原 See all SCARB1 蛋白
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    蛋白类型
    Recombinant
    产品特性
    AA 33-443
    宿主
    • 11
    • 4
    • 1
    资源
    • 9
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This SCARB1 protein is labelled with Fc Tag.
    序列
    AA 33-443
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.6 kDa. As a result of glycosylation, the protein migrates as 110-115 kDa under reducing (R) condition, and 220-230 kDa under non-reducing (NR) condition (SDS-PAGE).
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SCARB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    别名
    SCARB1 (SCARB1 产品)
    别名
    cb1015 Protein, SCARB1 Protein, Scarb1 Protein, CD36L1 Protein, CLA-1 Protein, CLA1 Protein, HDLQTL6 Protein, SR-BI Protein, SRB1 Protein, AI120173 Protein, CD36 Protein, Cd36l1 Protein, Cla-1 Protein, Cla1 Protein, D5Ertd460e Protein, Hdlq1 Protein, Hlb398 Protein, SR-B1 Protein, SRBI Protein, Srb1 Protein, mSR-BI Protein, scavenger receptor class B, member 1 Protein, scavenger receptor class B member 1 Protein, scarb1 Protein, SCARB1 Protein, Scarb1 Protein, CpipJ_CPIJ014332 Protein, CpipJ_CPIJ019101 Protein
    背景
    Scavenger receptor class B member 1 (SRB1) is also known as SR-BI, CD36 and LIMPII analogous 1 (CD36L1), CLA-1, is a member of the scavenger receptor family or CD36 family. CD36L1 is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. SRB1 is receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. CLA-1 facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high-density lipoprotein (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. SCARB1 is, along with CD81, the receptor for the entry of the Hepatitis C virus glycoprotein E2 in liver cells, and binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. SRB1 plays an important role in the uptake of HDL cholesteryl ester.
    分子量
    72.7 kDa
    NCBI登录号
    NP_005496
    途径
    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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