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SCARB1 Protein (His tag,Fc Tag)

SCARB1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320320
发货至: 中国
  • 抗原 See all SCARB1 蛋白
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    蛋白类型
    Recombinant
    宿主
    • 12
    • 3
    • 1
    小鼠
    资源
    • 9
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This SCARB1 protein is labelled with His tag,Fc Tag.
    原理
    Recombinant Mouse SR-BI/CD36L1 Protein (His & Fc Tag)
    序列
    Pro 33-Val 440
    产品特性
    A DNA sequence encoding the mature form of mouse SRB1 (NP_058021.1) extracellular domain (Pro 33-Val 440) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product SCARB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    别名
    SR-BI/CD36L1 (SCARB1 产品)
    别名
    cb1015 Protein, SCARB1 Protein, Scarb1 Protein, CD36L1 Protein, CLA-1 Protein, CLA1 Protein, HDLQTL6 Protein, SR-BI Protein, SRB1 Protein, AI120173 Protein, CD36 Protein, Cd36l1 Protein, Cla-1 Protein, Cla1 Protein, D5Ertd460e Protein, Hdlq1 Protein, Hlb398 Protein, SR-B1 Protein, SRBI Protein, Srb1 Protein, mSR-BI Protein, scavenger receptor class B, member 1 Protein, scavenger receptor class B member 1 Protein, scarb1 Protein, SCARB1 Protein, Scarb1 Protein, CpipJ_CPIJ014332 Protein, CpipJ_CPIJ019101 Protein
    背景

    Background: Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane. SCARB1 is proposed as a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells, and is involved in a wide variety of physilogical processes. As a key component in the reverse cholesterol transport pathway, SCARB1 binds high density lipoproteins (HDLs) and mediates selective cholesterol uptake by a mechanism distinct from the LDL pathway. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SCARB1 may thus serve as a useful marker that predicts variation in baseline lipid levels and postprandial lipid response. The mouse SCARB1 has been shown to exert actions in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

    Synonym: AI120173;CD36;Cd36l1;Cla-1;Cla1;D5Ertd460e;Hdlq1;Hlb398;mSR-BI;SR-B1;SR-BI;Srb1;SRBI

    分子量
    74 kDa
    NCBI登录号
    NP_058021
    途径
    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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