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IFNAR2 Protein (AA 27-243) (Fc Tag)

IFNAR2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181255
发货至: 中国
  • 抗原 See all IFNAR2 蛋白
    IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
    蛋白类型
    Recombinant
    产品特性
    AA 27-243
    宿主
    • 15
    • 5
    • 1
    • 1
    资源
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IFNAR2 protein is labelled with Fc Tag.
    序列
    AA 27-243
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.4 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IFNAR2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
    别名
    IFNAR2 (IFNAR2 产品)
    别名
    AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein
    背景
    Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection.
    分子量
    51.4 kDa
    NCBI登录号
    NP_997467
    途径
    JAK/STAT Signaling, Hepatitis C
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