IFNAR2 Protein (His tag)
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- 抗原 See all IFNAR2 蛋白
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This IFNAR2 protein is labelled with His tag.
- 原理
- Recombinant Human IFNAR2 Protein (His Tag)
- 序列
- Ile27-Lys243
- 产品特性
- Recombinant Human Interferon alpha/beta Receptor 2 is produced by our Mammalian expression system and the target gene encoding Ile27-Lys243 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IFNAR2 蛋白
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Interferon alpha/beta Receptor 2 (IFNAR2) (AA 144-243) protein (GST tag)
IFNAR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 264-513) protein (His tag)Crystallography grade IFNAR2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 265-515) protein (His tag)Crystallography grade IFNAR2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 27-243) protein (His tag)Crystallography grade IFNAR2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 22-242) protein (His tag)Crystallography grade IFNAR2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 27-515) protein (rho-1D4 tag)Crystallography grade IFNAR2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 22-513) protein (rho-1D4 tag)Crystallography grade IFNAR2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
- 别名
- IFNAR2 (IFNAR2 产品)
- 别名
- AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein
- 背景
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Background: Interferon α/β Receptor 2 (IFN-α/β R2) is a single-pass type I membrane protein which belongs to the type II cytokine receptor family. It complexes with IFN-α/β R1 to form the signaling receptor complex for the family of α and β IFN subtypes. By alternative splicing, IFN-α/β R2 can exist as a secreted soluble protein or as a type I membrane protein. IFN-α/β R2 is the principal ligand binding subunit of the receptor. Ligand binding is stabilized by the subsequent association with IFN-α/β R1, resulting in the formation of a signaling ternary receptor complex. IFNAR2 was detected in most lymphocytes, monocytes, and granulocytes, although IFNAR2 expression was higher in the monocytes and granulocytes than in the lymphocytes. Among the lymphocyte subsets, IFNAR2 showed high expression in natural killer (NK) cells and low expression in T lymphocytes. Isoform 1 and isoform 3 of IFNAR2 are directly involved in signal transduction due to their interaction with the TYR kinase, JAK1. Isoform 1 also interacts with the transcriptional factors, STAT1 and STAT2. Both forms are potent inhibitors of type I IFN activity.
Synonym: Interferon Alpha/Beta Receptor 2, IFN-R-2, IFN-Alpha Binding Protein, IFN-Alpha/Beta Receptor 2, Interferon Alpha Binding Protein, Type I Interferon Receptor 2, IFNAR2, IFNABR, IFNARB
- 分子量
- 25.8 kDa
- UniProt
- P48551
- 途径
- JAK/STAT Signaling, Hepatitis C
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