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Ephrin A1 Protein (EFNA1) (AA 19-182) (Fc Tag)

EFNA1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2180992
发货至: 中国
  • 抗原 See all Ephrin A1 (EFNA1) 蛋白
    Ephrin A1 (EFNA1)
    蛋白类型
    Recombinant
    产品特性
    AA 19-182
    宿主
    • 14
    • 4
    • 3
    • 1
    • 1
    资源
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Ephrin A1 protein is labelled with Fc Tag.
    序列
    AA 19-182
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46 kDa. As a result of glycosylation, the protein migrates as 50-55 kDa under reducing (R) condition, and 100-110 kDa under non-reducing (NR) condition (SDS-PAGE).
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product EFNA1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Swidergall, Solis, Millet, Huang, Lin, Phan, Lazarus, Wang, Yeaman, Mitchell, Filler: "Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors." in: PLoS pathogens, Vol. 17, Issue 1, pp. e1009221, (2021) (PubMed).

  • 抗原
    Ephrin A1 (EFNA1)
    别名
    Ephrin-A1 (EFNA1 产品)
    别名
    Xefrin-A1 Protein, b61 Protein, ecklg Protein, efl1 Protein, efna1 Protein, efna1a Protein, elfa-a Protein, epha1 Protein, eplg1 Protein, lerk1 Protein, tnfaip4 Protein, xelf-a' Protein, xelfa Protein, AI325262 Protein, B61 Protein, Efl1 Protein, Epl1 Protein, Eplg1 Protein, Lerk1 Protein, ECKLG Protein, EFL1 Protein, EPLG1 Protein, LERK-1 Protein, LERK1 Protein, TNFAIP4 Protein, efna1b Protein, MGC130661 Protein, ephrin-A1 S homeolog Protein, ephrin-A1 Protein, ephrin A1 Protein, ephrin-A1b Protein, ephrin-A1 L homeolog Protein, efna1.S Protein, efna1 Protein, EFNA1 Protein, efna1b Protein, Efna1 Protein, efna1.L Protein
    背景
    Ephrin-A1 (EFNA1) is also known as EPLG1, LERK1, TNFAIP4, Immediate early response protein B61, which belongs to the ephrin family. EFNA1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA1 is cell surface GPI-bound ligand for Eph receptors, and is a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA1 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA1 plays an important role in angiogenesis and tumor neovascularization.
    分子量
    46.0 kDa
    NCBI登录号
    NP_004419
    途径
    RTK signaling
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