CD79b Protein (AA 29-159) (Fc Tag)
(1 reference)-
- 抗原 See all CD79b (CD79B) 蛋白
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 29-159
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD79b protein is labelled with Fc Tag.
- 序列
- AA 29-159
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.8 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product CD79B 蛋白
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CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 29-159) protein (His-Avi Tag)
CD79B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 29-159) protein (His-Avi Tag,Biotin)CD79B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 29-159) protein (Fc Tag)CD79B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 26-158) protein (His tag)CD79B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 1-229) protein (GST tag)CD79B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) protein (His tag)CD79B 宿主: 猕猴 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) protein (Fc Tag)CD79B 宿主: 猕猴 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) protein (Fc Tag)CD79B 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) protein (His tag)CD79B 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) protein (Fc Tag)CD79B 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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: "Targeting CD79b for Chimeric Antigen Receptor T-Cell Therapy of B-Cell Lymphomas." in: Targeted oncology, Vol. 15, Issue 3, pp. 365-375, (2020) (PubMed).
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: "Targeting CD79b for Chimeric Antigen Receptor T-Cell Therapy of B-Cell Lymphomas." in: Targeted oncology, Vol. 15, Issue 3, pp. 365-375, (2020) (PubMed).
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- 抗原
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- 别名
- CD79B (CD79B 产品)
- 别名
- B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein
- 背景
- B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
- 分子量
- 41.8 kDa
- NCBI登录号
- NP_000617
- 途径
- BCR Signaling
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