Selectin E/CD62e Protein (AA 22-556) (Fc Tag)
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- 抗原 See all Selectin E/CD62e (SELE) 蛋白
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-556
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Selectin E/CD62e protein is labelled with Fc Tag.
- 序列
- AA 22-556
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 84.8 kDa. The protein migrates as 150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product SELE 蛋白
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Selectin E (SELE) (AA 22-556) protein (His-Avi Tag)
SELE 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin E (SELE) (AA 22-556) protein (Fc Tag)SELE 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin E (SELE) (AA 22-554) protein (His tag)SELE 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin E (SELE) protein (His-Avi Tag,Biotin)SELE 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Selectin E (SELE) (AA 22-557) protein (His tag)SELE 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin E (SELE) (AA 1-610) protein (GST tag)SELE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Selectin E (SELE) (AA 401-500) protein (GST tag)SELE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Selectin E (SELE) (Active) protein (His tag)SELE 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Selectin E (SELE) (Active) protein (Fc Tag)SELE 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Selectin E (SELE) (Active) protein (Fc Tag)SELE 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- 抗原
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- 别名
- E-Selectin (SELE 产品)
- 别名
- SELE Protein, CD62E Protein, ELAM Protein, ELAM1 Protein, ESEL Protein, LECAM2 Protein, E-selectin Protein, Elam Protein, selectin E Protein, selectin, endothelial cell Protein, SELE Protein, Sele Protein
- 背景
- E-Selectin is also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), a member of the Selectin family, is a 107-115 kDa cell surface glycoprotein.[1] It is transiently expressed on vascular endothelial cells in response to IL-1β and TNFα. E selectin has a cassette structure: an N-terminal, C-type lectin domain, an EGF (epidermal-growth-factor)-like domain, 6 Sushi domain (SCR repeat) units, a transmembrane domain (TM) and an intracellular cytoplasmic tail (cyto).[2] During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. The local release of cytokines IL-1 and TNF-α by damaged cells induces the over-expression of E-selectin on endothelial cells of nearby blood vessels.[3] E-selectin mediates the adhesion of tumor cells to endothelial cells, by binding to E-selectin ligands expressed by neutrophils, monocytes, eosinophils, memory-effector T-like lymphocytes, natural killer cells or cancer cells. Furthermore, a number of studies have reported that levels of E-Selectin may be elevated in subjects with a variety of pathological conditions.
- 分子量
- 84.8 kDa
- NCBI登录号
- NP_000441
- 途径
- Thromboxane A2 Receptor Signaling
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